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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
21.82
Human Site:
Y375
Identified Species:
36.92
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
Y375
E
R
R
P
S
K
R
Y
S
R
R
T
L
Q
M
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
Y375
E
R
R
P
S
K
R
Y
S
R
R
T
L
Q
M
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
T365
T
N
K
A
R
R
S
T
S
F
E
R
R
P
S
Dog
Lupus familis
XP_532028
914
101864
Y457
E
R
K
P
S
K
R
Y
P
S
R
R
H
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
Y375
E
R
R
P
S
K
R
Y
S
R
R
T
L
Q
M
Rat
Rattus norvegicus
Q5FVG2
731
81700
Y375
E
R
R
P
S
K
R
Y
S
R
R
T
L
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
C375
G
A
G
Q
D
R
K
C
V
P
N
K
D
L
L
Chicken
Gallus gallus
XP_422083
502
57358
S149
Q
L
K
L
D
I
L
S
G
K
L
E
C
P
F
Frog
Xenopus laevis
NP_001080234
498
57093
Q145
L
F
V
L
Q
L
K
Q
D
I
L
S
G
K
L
Zebra Danio
Brachydanio rerio
O57457
619
70690
C266
L
R
V
L
G
R
D
C
N
E
T
S
F
F
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
F390
E
R
R
P
S
Q
R
F
A
S
R
Q
S
H
L
Honey Bee
Apis mellifera
XP_623974
809
90976
Y455
E
R
R
P
S
Q
R
Y
A
R
R
Q
S
H
V
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
A536
Q
P
T
S
T
T
N
A
S
Y
S
P
Y
L
N
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
F370
E
R
R
P
S
Q
R
F
S
R
R
P
S
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
6.6
53.3
N.A.
100
93.3
N.A.
0
0
0
6.6
N.A.
46.6
60
6.6
60
P-Site Similarity:
100
100
20
60
N.A.
100
100
N.A.
20
20
26.6
26.6
N.A.
73.3
80
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
8
15
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
15
0
8
0
8
0
0
0
8
0
0
% D
% Glu:
58
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
15
0
8
0
0
8
8
15
% F
% Gly:
8
0
8
0
8
0
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
15
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
22
0
0
36
15
0
0
8
0
8
0
8
0
% K
% Leu:
15
8
0
22
0
8
8
0
0
0
15
0
29
15
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% M
% Asn:
0
8
0
0
0
0
8
0
8
0
8
0
0
0
8
% N
% Pro:
0
8
0
58
0
0
0
0
8
8
0
15
0
15
0
% P
% Gln:
15
0
0
8
8
22
0
8
0
0
0
15
0
29
0
% Q
% Arg:
0
65
50
0
8
22
58
0
0
43
58
15
8
0
0
% R
% Ser:
0
0
0
8
58
0
8
8
50
15
8
15
22
8
8
% S
% Thr:
8
0
8
0
8
8
0
8
0
0
8
29
0
0
8
% T
% Val:
0
0
15
0
0
0
0
0
8
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
8
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _